Invitrogen™ MRPL23 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109978

Catalog No. PIPA5109978

Description

Immunogen sequence: MARNVVYPLY RLGGPQLRVF RTNFFIQLVR PGVAQPEDTV QFRIPMEMTR VDLRNYLEGI YNVPVAAVRT RVQHGSNKRR DHRNVRIKKP DYKVAYVQLA HGQTFTFPDL FPEKDESPEG SAADDLYSML EEERQQRQSS DPRRGGVPSW FGL.

MRPL23 are mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL23 encodes a 39S subunit protein and is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11.

Specifications

• Antigen: MRPL23
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL23
• Gene Alias: 39S ribosomal protein L23, mitochondrial; FLJ45387; L23 mitochondrial-related protein; L23mrp; L23mt; Mitochondrial large ribosomal subunit protein uL23m; mitochondrial ribosomal protein L23; Mrpl23; MRP-L23; Ribosomal protein L23-like; ribosomal protein L23-related product homolog; ribosomal protein related to L23 (mitochondrial); rL23MRP; Rpl23; RPL23L; Rpl23-rs
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19935, 6150, 64360
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.81 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O35972, Q16540, Q63750
• Gene Symbols: MRPL23
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-153 of human MRPL23 (NP_066957.3).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG