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Invitrogen™ MRPL28 Polyclonal Antibody
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Catalog No. PIPA5103523
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PIPA5103523 100 μL
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Catalog No. PIPA5103523 Supplier Invitrogen™ Supplier No. PA5103523
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MRPL28.

MRP-L28 (39S ribosomal protein L28, melanoma-associated antigen recognized by T lymphocytes) is a mitochondrial protein that belongs to the ribosomal protein L28P family. MRP-L28 potentially represents an important therapeutic reagent for HLA-A24 (A24) patients as this antigen is recognized by tumor-infiltrating lymphocyte (TIL) 1290, which targets the A24 serotype. HLAA24 (A24) is an HLA-A serotype that identifies the more common HLA-A24 gene products. A24 is a split antigen that is also recognized by the A9 broad antigen type and the similar A23 types. A24 is common in Austronesia and has one of the highest A allele frequencies for a number of peoples, including Papua New Guineans, indigeonous Taiwanese (eastern tribals), Yupik and Greenland Eskimos. MRP-L28 is found in a variety of normal tissues including spleen, testis, thymus, liver, kidney, brain, adrenal, lung and retinal tissue.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRPL28
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MRPL28
Gene Accession No. Q13084, Q9D1B9
Gene Alias 1110015G04Rik; 39S ribosomal protein L28, mitochondrial; HGNC6756; L28mt; MAAT 1; MAAT1; Melanoma antigen p15; melanoma-associated antigen recognised by cytotoxic T lymphocytes; melanoma-associated antigen recognized by T lymphocytes; melanoma-associated antigen recognized by T-lymphocytes; MGC8499; Mitochondrial large ribosomal subunit protein bL28m; mitochondrial ribosomal protein L28; MRP L28; MRPL 28; MRPL28; MRP-L28; p15
Gene Symbols MRPL28
Host Species Rabbit
Immunogen A synthesized peptide derived from human MRPL28(Accession Q13084), corresponding to amino acid residues L146-I196.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10573, 68611
Target Species Human, Mouse, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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