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Invitrogen™ MRPL28 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA576846
Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
MRP-L28 (39S ribosomal protein L28, melanoma-associated antigen recognized by T lymphocytes) is a mitochondrial protein that belongs to the ribosomal protein L28P family. MRP-L28 potentially represents an important therapeutic reagent for HLA-A24 (A24) patients as this antigen is recognized by tumor-infiltrating lymphocyte (TIL) 1290, which targets the A24 serotype. HLAA24 (A24) is an HLA-A serotype that identifies the more common HLA-A24 gene products. A24 is a split antigen that is also recognized by the A9 broad antigen type and the similar A23 types. A24 is common in Austronesia and has one of the highest A allele frequencies for a number of peoples, including Papua New Guineans, indigeonous Taiwanese (eastern tribals), Yupik and Greenland Eskimos. MRP-L28 is found in a variety of normal tissues including spleen, testis, thymus, liver, kidney, brain, adrenal, lung and retinal tissue.
Specifications
MRPL28 | |
Polyclonal | |
Unconjugated | |
MRPL28 | |
1110015G04Rik; 39S ribosomal protein L28, mitochondrial; HGNC6756; L28mt; MAAT 1; MAAT1; Melanoma antigen p15; melanoma-associated antigen recognised by cytotoxic T lymphocytes; melanoma-associated antigen recognized by T lymphocytes; melanoma-associated antigen recognized by T-lymphocytes; MGC8499; Mitochondrial large ribosomal subunit protein bL28m; mitochondrial ribosomal protein L28; MRP L28; MRPL 28; MRPL28; MRP-L28; p15 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
10573, 497876 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
Q13084 | |
MRPL28 | |
Recombinant full length Human MRPL28. | |
100 μL | |
Primary | |
Human, Rat | |
Antibody | |
IgG |
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