Invitrogen™ MRPL3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106677

Catalog No. PIPA5106677

Description

Antibody detects endogenous levels of total MRPL3.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q.

Specifications

• Antigen: MRPL3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL3
• Gene Alias: 2010320L16Rik; 39S ribosomal protein L3, mitochondrial; 5930422H18Rik; AA407889; COXPD9; L3mt; mitochondrial 60S ribosomal protein L3; Mitochondrial large ribosomal subunit protein uL3m; mitochondrial ribosomal protein L3; MRL3; Mrpl3; MRP-L3; RPML3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11222
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P09001
• Gene Symbols: MRPL3
• Immunogen: A synthesized peptide derived from human MRPL3(Accession P09001), corresponding to amino acid residues G43-G93.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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