Invitrogen™ MRPL39 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531983

Catalog No. PIPA531983

Description

Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Mouse (93%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.

Specifications

• Antigen: MRPL39
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL39
• Gene Alias: 39S ribosomal protein L39, mitochondrial; 39S ribosomal protein L5, mitochondrial; C21orf8; C21orf92; L39mt; L5mt; Mitochondrial large ribosomal subunit protein mL39; mitochondrial ribosomal protein L39; MRPL39; MRP-L39; MRPL5; MRP-L5; MSTP003; ORF22; PRED22; PRED66; ribosomal protein, mitochondrial, L5; RPML5
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54148
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9NYK5
• Gene Symbols: MRPL39
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 208 of Human MRPL39.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov