Invitrogen™ MRPL39 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553785

Catalog No. PIPA553785

Description

Immunogen sequence: ERIVKLHRIG DFIDVSEGPL IPRTSICFQY EVSAVHNLQP TQPSLIRRFQ GVSLPVHLRA HFTIWDKLLE RSRKMVTEDQ SKAT Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.

Specifications

• Antigen: MRPL39
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL39
• Gene Alias: 39S ribosomal protein L39, mitochondrial; 39S ribosomal protein L5, mitochondrial; C21orf8; C21orf92; L39mt; L5mt; Mitochondrial large ribosomal subunit protein mL39; mitochondrial ribosomal protein L39; MRPL39; MRP-L39; MRPL5; MRP-L5; MSTP003; ORF22; PRED22; PRED66; ribosomal protein, mitochondrial, L5; RPML5
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27393, 54148, 684304
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9JKF7, Q9NYK5
• Gene Symbols: MRPL39
• Immunogen: Recombinant protein corresponding to Human MRPL39. Recombinant protein control fragment (Product #RP-91811).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG