Invitrogen™ MRPL40 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551012

Catalog No. PA551012

Description

MRPL40 Polyclonal Antibody detects endogenous levels of MRPL40 protein.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.

Specifications

• Antigen: MRPL40
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL40
• Gene Alias: 39S ribosomal protein L40, mitochondrial; L40mt; Mitochondrial large ribosomal subunit protein mL40; mitochondrial ribosomal protein L40; MRPL22; MRP-L22; Mrpl40; MRP-L40; Nlvcf; nuclear localization signal protein absent in velo-cardio-facial patients; nuclear localization signal-containing protein deleted in velocardiofacial syndrome; Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog; up-regulated in metastasis; URIM
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64976
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9NQ50
• Gene Symbols: MRPL40
• Immunogen: Synthesized peptide derived from the Internal region of human MRP-L40 (aa 101-150).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG