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Invitrogen™ MRPL40 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA552265
Description
Immunogen sequence: TQLRETQELI PIEDFITPLK FLDKARERPQ VELTFEETER RALLLKKWSL YKQQERKMER DTIRAMLEAQ QEALEELQLE SPKLHAEAIK RDPNLFPFEK EGPHYTPPIP NYQPPEGRYN DITK Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 77%.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.
Specifications
MRPL40 | |
Polyclonal | |
Unconjugated | |
MRPL40 | |
39S ribosomal protein L40, mitochondrial; L40mt; Mitochondrial large ribosomal subunit protein mL40; mitochondrial ribosomal protein L40; MRPL22; MRP-L22; Mrpl40; MRP-L40; Nlvcf; nuclear localization signal protein absent in velo-cardio-facial patients; nuclear localization signal-containing protein deleted in velocardiofacial syndrome; Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog; up-regulated in metastasis; URIM | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
18100, 287962, 64976 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.2 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
P83565, Q9NQ50, Q9Z2Q5 | |
MRPL40 | |
Recombinant protein corresponding to Human MRPL40. Recombinant protein control fragment (Product #RP-91336). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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