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Invitrogen™ MRPL40 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552265

Catalog No. PIPA552265


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Description

Description

Immunogen sequence: TQLRETQELI PIEDFITPLK FLDKARERPQ VELTFEETER RALLLKKWSL YKQQERKMER DTIRAMLEAQ QEALEELQLE SPKLHAEAIK RDPNLFPFEK EGPHYTPPIP NYQPPEGRYN DITK Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 77%.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MRPL40
Polyclonal
Unconjugated
MRPL40
39S ribosomal protein L40, mitochondrial; L40mt; Mitochondrial large ribosomal subunit protein mL40; mitochondrial ribosomal protein L40; MRPL22; MRP-L22; Mrpl40; MRP-L40; Nlvcf; nuclear localization signal protein absent in velo-cardio-facial patients; nuclear localization signal-containing protein deleted in velocardiofacial syndrome; Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog; up-regulated in metastasis; URIM
Rabbit
Antigen affinity chromatography
RUO
18100, 287962, 64976
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.2 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
P83565, Q9NQ50, Q9Z2Q5
MRPL40
Recombinant protein corresponding to Human MRPL40. Recombinant protein control fragment (Product #RP-91336).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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