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Invitrogen™ MRPL43 Polyclonal Antibody
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Catalog No. PIPA5103527
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PIPA5103527 100 μL
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Catalog No. PIPA5103527 Supplier Invitrogen™ Supplier No. PA5103527
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MRPL43.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRPL43
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MRPL43
Gene Accession No. Q8N983, Q99N89
Gene Alias 39S ribosomal protein L43, mitochondrial; 4930442D21Rik; bMRP36a; L43mt; Mitochondrial large ribosomal subunit protein mL43; Mitochondrial ribosomal protein bMRP36a; mitochondrial ribosomal protein L43; MRPL43; MRP-L43; MRPL43 protein; putative; retina-specific 15.7 kDa protein
Gene Symbols MRPL43
Host Species Rabbit
Immunogen A synthesized peptide derived from human MRPL43(Accession Q8N983), corresponding to amino acid residues A152-C202.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 309440, 84545, 94067
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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