Invitrogen™ MRPL43 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116773

Catalog No. PIPA5116773

Description

Positive Samples: A-549, PC-3, 293T Immunogen sequence: LNGAVREESI HCKSVEEIST LVQKLADQSG LDVIRIRKPF HTDNPSIQGQ WHPFTNKPTT FRGLRPREVQ DPAPAQ.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms.

Specifications

• Antigen: MRPL43
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL43
• Gene Alias: 39S ribosomal protein L43, mitochondrial; 4930442D21Rik; bMRP36a; L43mt; Mitochondrial large ribosomal subunit protein mL43; Mitochondrial ribosomal protein bMRP36a; mitochondrial ribosomal protein L43; MRPL43; MRP-L43; MRPL43 protein; putative; retina-specific 15.7 kDa protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 309440, 84545, 94067
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.18 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q8N983, Q99N89
• Gene Symbols: MRPL43
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-155 of human MRPL43 (NP_7897621).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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