Invitrogen™ MRPL45 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA545104

Catalog No. PIPA545104

Description

Peptide sequence: YGSWRMHTKI VPPWAPPKQP ILKTVMIPGP QLKPEEEYEE AQGEAQKPQL Sequence homology: Cow: 75%; Human: 100%; Mouse: 91%; Rat: 82%; Zebrafish: 75%.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.

Specifications

• Antigen: MRPL45
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mrpl45
• Gene Alias: 2600005P05Rik; 39S ribosomal protein L45, mitochondrial; AU043542; L45mt; MGC11321; mitochondrial ribosomal protein L45; MRPL45; MRP-L45; R75241; Unknown (protein for MGC:127097); zgc:56480
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84311
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9BRJ2
• Gene Symbols: Mrpl45
• Immunogen: Synthetic peptide directed towards the C-terminal of human MRPL45 (aa 256-305).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG