Invitrogen™ MRPL47 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101365

Catalog No. PIPA5101365

Description

Antibody detects endogenous levels of total MRPL47.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identified.

Specifications

• Antigen: MRPL47
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL47
• Gene Alias: 39S ribosomal protein L47, mitochondrial; 4833424P18Rik; CGI-204; ENSMUSG00000051761; Gm9859; L47mt; metanephros-derived tubulogenic factor; Mitochondrial large ribosomal subunit protein uL29m; mitochondrial ribosomal protein L47; Mrpl47; MRP-L47; MTF/L47; nasopharyngeal carcinoma metastasis-related 1; nasopharyngeal carcinoma metastasis-related protein 1; NCM1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57129, 74600
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8K2Y7, Q9HD33
• Gene Symbols: MRPL47
• Immunogen: A synthesized peptide derived from human MRPL47, corresponding to a region within C-terminal amino acids.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG