Invitrogen™ MRPL47 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558002

Catalog No. PIPA558002

Description

Immunogen sequence: LKERNMLLTL EQEAKRQRLP MPSPERLDKV VDSMDALDKV VQEREDALRL LQTGQERARP GAWRRDIFGR IIWHKFKQWV I Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 93%.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identified.

Specifications

• Antigen: MRPL47
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL47
• Gene Alias: 39S ribosomal protein L47, mitochondrial; 4833424P18Rik; CGI-204; ENSMUSG00000051761; Gm9859; L47mt; metanephros-derived tubulogenic factor; Mitochondrial large ribosomal subunit protein uL29m; mitochondrial ribosomal protein L47; Mrpl47; MRP-L47; MTF/L47; nasopharyngeal carcinoma metastasis-related 1; nasopharyngeal carcinoma metastasis-related protein 1; NCM1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57129
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.6 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9HD33
• Gene Symbols: MRPL47
• Immunogen: Recombinant protein corresponding to Human MRPL47. Recombinant protein control fragment (Product #RP-96340).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG