Invitrogen™ MRPL48 Monoclonal Antibody (1H8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA521967

Catalog No. PIMA521967

Description

Peptide Sequence: MSGTLGKVLC LRNNTIFKQA FSLLRFRTSG EKPIYSVGGI LLSISRPYKT KPTHGIGKYK HLIKAEEPKK KKGKVEVRAI NLGTDYEYGV LNIHLTAYDM TLAESYAQYV HNLCNSLSIK VEESYAMPTK TIEVLQLQDQ GSKMLLDSVL TTHERVVQIS GLSATFAEIF LEIIQSSLPE GVRLSVKEHT EEDFKGRFKA RPELEELLAK LK.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p.

Specifications

• Antigen: MRPL48
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q96GC5
• Gene Symbols: MRPL48
• Immunogen: MRPL48 (AAH09764, 1 a.a. ~ 212 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA
• Clone: 1H8
• Conjugate: Unconjugated
• Gene: MRPL48
• Gene Alias: 1810030E20Rik; 2610028L11Rik; 39S ribosomal protein L48, mitochondrial; CGI-118; D4Ertd786e; HSPC290; L48mt; MGC13323; mitochondrial 39S ribosomal protein L48-like protein; Mitochondrial large ribosomal subunit protein mL48; mitochondrial ribosomal protein L48; Mrpl48; MRP-L48; Unknown (protein for MGC:133957)
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51642
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid