Invitrogen™ MRPL49 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561321

Catalog No. PIPA561321

Description

Immunogen sequence: GKTPVTQVNE VTGTLRIKGY FDQELKAWLL EKGF Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 94%.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for the HRD1 protein use in their respective 3' UTRs some of the same genomic sequence. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p.

Specifications

• Antigen: MRPL49
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL49
• Gene Alias: 39S ribosomal protein L49, mitochondrial; 4833419D18Rik; Aa2-277; C11orf4; L49mt; MGC10656; Mitochondrial large ribosomal subunit protein mL49; mitochondrial ribosomal protein L49; Mrpl49; MRP-L49; Neighbor of FAU; neighbor of fau 1; next to FAU; NOF; NOF1; OK/SW-cl.67; Protein NOF1; Unknown (protein for MGC:142600)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 740
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q13405
• Gene Symbols: MRPL49
• Immunogen: Recombinant protein corresponding to Human MRPL49. Recombinant protein control fragment (Product #RP-100660).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov