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Invitrogen™ MRPL49 Polyclonal Antibody
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Catalog No. PIPA5106679
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PIPA5106679 100 μL
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Catalog No. PIPA5106679 Supplier Invitrogen™ Supplier No. PA5106679
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MRPL49.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for the HRD1 protein use in their respective 3' UTRs some of the same genomic sequence. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRPL49
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MRPL49
Gene Accession No. Q13405, Q9CQ40
Gene Alias 39S ribosomal protein L49, mitochondrial; 4833419D18Rik; Aa2-277; C11orf4; L49mt; MGC10656; Mitochondrial large ribosomal subunit protein mL49; mitochondrial ribosomal protein L49; Mrpl49; MRP-L49; Neighbor of FAU; neighbor of fau 1; next to FAU; NOF; NOF1; OK/SW-cl.67; Protein NOF1; Unknown (protein for MGC:142600)
Gene Symbols MRPL49
Host Species Rabbit
Immunogen A synthesized peptide derived from human MRPL49(Accession Q13405), corresponding to amino acid residues D34-Y84.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18120, 740
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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