Invitrogen™ MRPL49 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5112889

Catalog No. PIPA5112889

Description

MRPL49 Polyclonal Antibody for Western Blot, IHC (P), ELISA

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for the HRD1 protein use in their respective 3' UTRs some of the same genomic sequence. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p.

Specifications

• Antigen: MRPL49
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL49
• Gene Alias: 39S ribosomal protein L49, mitochondrial; 4833419D18Rik; Aa2-277; C11orf4; L49mt; MGC10656; Mitochondrial large ribosomal subunit protein mL49; mitochondrial ribosomal protein L49; Mrpl49; MRP-L49; Neighbor of FAU; neighbor of fau 1; next to FAU; NOF; NOF1; OK/SW-cl.67; Protein NOF1; Unknown (protein for MGC:142600)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18120, 740
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.3 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q13405, Q9CQ40
• Gene Symbols: MRPL49
• Immunogen: Recombinant Human 39S ribosomal protein L49, mitochondrial protein (1-166AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG