Invitrogen™ MRPL57 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558926

Catalog No. PIPA558926

Description

Immunogen sequence: RFVSLRAKQN MIRRLEIEAE NHYWLSMPYM TREQERGHAA VRRREAFEAI KA Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 81%.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein which belongs to an undetermined ribosomal subunit and which seems to be specific to animal mitoribosomes. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 3p, 5q, 8q, 14q, and Y.

Specifications

• Antigen: MRPL57
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL57
• Gene Alias: bMRP63; hMRP63; Mitochondrial large ribosomal subunit protein mL63; Mitochondrial ribosomal protein 63; mitochondrial ribosomal protein bMRP63; mitochondrial ribosomal protein L57; MRP63; MRPL57; Ribosomal protein 63, mitochondrial
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 78988
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BQC6
• Gene Symbols: MRPL57
• Immunogen: Recombinant protein corresponding to Human MRPL57. Recombinant protein control fragment (Product #RP-97994).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG