MRPS11 Monoclonal Antibody (OTI2E6), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA802877

Catalog No. 50-167-9461

Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: MRPS11
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P82912
• Gene Symbols: MRPS11
• Immunogen: Full length human recombit protein of human MRPS11 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: OTI2E6
• Conjugate: Unconjugated
• Gene: MRPS11
• Gene Alias: HCC-2, MRP-S11, S11mt
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64963
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid