Invitrogen™ MRPS15 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115592

Catalog No. PIPA5115592

Description

Antibody detects endogenous levels of total MRPS15.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS15 encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q.

Specifications

• Antigen: MRPS15
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPS15
• Gene Alias: 1500003E24Rik; 2410002B11Rik; 28S ribosomal protein S15, mitochondrial; DC37; FLJ11564; mitochondrial ribosomal protein S15; Mitochondrial small ribosomal subunit protein uS15m; Mprs15; MPR-S15; Mrps15; MRP-S15; RPMS15; S15mt
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 298517, 64960, 66407
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P82914, Q5XI37, Q9DC71
• Gene Symbols: MRPS15
• Immunogen: A synthesized peptide derived from human MRPS15(Accession P82914), corresponding to amino acid residues A117-L167.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG