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Invitrogen™ MRPS18A Polyclonal Antibody
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Catalog No. PIPA557274
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100 μL
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PIPA557274 100 μL
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Catalog No. PIPA557274 Supplier Invitrogen™ Supplier No. PA557274
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PSELQRELQR LSPLPRHSGL LPNHRPRLPE GVVPKSKPQL NRYLTRWAPG SVKPIYKKGP RWNRVRMPVG SPLLRDNVCY SRTPWKLYH Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 64%.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. A pseudogene corresponding to this gene is found on chromosome 3p. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRPS18A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Mrps18a
Gene Accession No. Q9NVS2
Gene Alias 1110004O20Rik; 28S ribosomal protein S18-3, mitochondrial; 28S ribosomal protein S18a, mitochondrial; 39S ribosomal protein S18-3, mitochondrial; 39S ribosomal protein S18a, mitochondrial; C79712; HumanS18b; Mitochondrial large ribosomal subunit protein bS18a; Mitochondrial large ribosomal subunit protein mL66; mitochondrial ribosomal protein S18-3; mitochondrial ribosomal protein S18A; MRP-S18-3; MRPS18-3; MRPS18A; MRP-S18-a; S18bmt; S18mt-a
Gene Symbols Mrps18a
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MRPS18A. Recombinant protein control fragment (Product #RP-94658).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55168
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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