Invitrogen™ MRPS18A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113436

Catalog No. PIPA5113436

Description

MRPS18A Polyclonal Antibody for Western Blot, ELISA

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. A pseudogene corresponding to this gene is found on chromosome 3p. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: MRPS18A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mrps18a
• Gene Alias: 1110004O20Rik; 28S ribosomal protein S18-3, mitochondrial; 28S ribosomal protein S18a, mitochondrial; 39S ribosomal protein S18-3, mitochondrial; 39S ribosomal protein S18a, mitochondrial; C79712; HumanS18b; Mitochondrial large ribosomal subunit protein bS18a; Mitochondrial large ribosomal subunit protein mL66; mitochondrial ribosomal protein S18-3; mitochondrial ribosomal protein S18A; MRP-S18-3; MRPS18-3; MRPS18A; MRP-S18-a; S18bmt; S18mt-a
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 55168
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 3 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q9NVS2
• Gene Symbols: Mrps18a
• Immunogen: Recombinant Human 39S ribosomal protein S18a, mitochondrial protein (1-196AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov