Invitrogen™ MRPS18B Polyclonal Antibody

Catalog No.	Quantity
PIPA5103515	100 μL

Catalog No. PIPA5103515

Supplier: Invitrogen™ PA5103515

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MRPS18B.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.

Specifications

• Antigen: MRPS18B
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: MRPS18B
• Gene Accession No.: Q99N84, Q9Y676
• Gene Alias: 2400002C15Rik; 28S ribosomal protein S18-2, mitochondrial; 28S ribosomal protein S18b, mitochondrial; C6orf14; HSPC183; HumanS18a; mitochondrial ribosomal protein S18-2; mitochondrial ribosomal protein S18B; Mitochondrial small ribosomal subunit protein bS18b; Mitochondrial small ribosomal subunit protein mS40; MRP-S18-2; MRPS18-2; MRPS18B; MRP-S18-b; mrps18-b; PTD017; S18amt; S18mt-b
• Gene Symbols: MRPS18B
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human MRPS18B(Accession Q9Y676), corresponding to amino acid residues E66-D116.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 28973, 294230, 66973
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG