Invitrogen™ MRPS18C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101348

Catalog No. PIPA5101348

Description

Antibody detects endogenous levels of total MRPS18C.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q. [provided by RefSeq, Jul 2008].

Specifications

• Antigen: MRPS18C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPS18C
• Gene Alias: 1110037D14Rik; 28S ribosomal protein S18-1, mitochondrial; 28S ribosomal protein S18c, mitochondrial; CGI-134; mitochondrial ribosomal protein S18-1; mitochondrial ribosomal protein S18C; Mitochondrial small ribosomal subunit protein bS18c; Mitochondrial small ribosomal subunit protein bS18m; MRP-S18-1; MRPS18-1; MRPS18C; MRP-S18-c; mrps18-c; S18mt-c
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 289469, 51023, 68735
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8R2L5, Q9Y3D5
• Gene Symbols: MRPS18C
• Immunogen: A synthesized peptide derived from human MRPS18C(Accession Q9Y3D5), corresponding to amino acid residues S81-K131.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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