Invitrogen™ MRPS30 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596444

Catalog No. PIPA596444

Description

Immunogen sequence: PHNPALAAAA LDYRCPVHFY WVRGEEIIPR GHRRGRIDDL RYQIDDKPNN QIRISKQLAE FVPLDYSVPI EIPTIKCKPD KLPLFKRQYE NHIFVGSKTA DPCCYGHTQF HLLPDKLRRE RLLRQNCADQ IEVVFRANAI ASLFAWTGAQ AMYQGFWSEA DVTRPFVSQA VITDGKYFSF FCYQLNTLAL TTQADQNNPR KNICWGTQSK PLYETIEDND VKGFNDDVLL QIVHFLLNRP KEEKSQLLEN; Positive Samples: SW620, HL-60, HeLa, HepG2; Cellular Location: Mitochondrion.

Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-S30 (mitochondrial ribosomal protein S30), also known as PDCD9 (programmed cell death protein 9), is a 439 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 28S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. MRP-S30 is expressed in kidney, liver, heart and skeletal muscle. The gene encoding MRP-S30 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Specifications

• Antigen: MRPS30
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mrps30
• Gene Alias: 2610020A16Rik; 28S ribosomal protein S30, mitochondrial; 39S ribosomal protein S30, mitochondrial; AA968347; BM-047; Mitochondrial large ribosomal subunit protein mL65; Mitochondrial large ribosomal subunit protein mS30; mitochondrial ribosomal protein S30; MRP S30; Mrps30; MRP-S30; PAP; PDCD9; programmed cell death 9; Programmed cell death protein 9; S30mt
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10884, 294767, 59054
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.89 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9D0G0, Q9NP92
• Gene Symbols: Mrps30
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 190-439 of human MRPS30 (NP_0577242).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov