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Invitrogen™ MRPS30 Polyclonal Antibody
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Catalog No. PIPA5101669
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PIPA5101669 100 μL
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Catalog No. PIPA5101669 Supplier Invitrogen™ Supplier No. PA5101669
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MRPS30.

Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-S30 (mitochondrial ribosomal protein S30), also known as PDCD9 (programmed cell death protein 9), is a 439 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 28S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. MRP-S30 is expressed in kidney, liver, heart and skeletal muscle. The gene encoding MRP-S30 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRPS30
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Mrps30
Gene Accession No. Q9D0G0, Q9NP92
Gene Alias 2610020A16Rik; 28S ribosomal protein S30, mitochondrial; 39S ribosomal protein S30, mitochondrial; AA968347; BM-047; Mitochondrial large ribosomal subunit protein mL65; Mitochondrial large ribosomal subunit protein mS30; mitochondrial ribosomal protein S30; MRP S30; Mrps30; MRP-S30; PAP; PDCD9; programmed cell death 9; Programmed cell death protein 9; S30mt
Gene Symbols Mrps30
Host Species Rabbit
Immunogen A synthesized peptide derived from human MRPS30(Accession Q9NP92), corresponding to amino acid residues Q382-E432.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10884, 59054
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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