Invitrogen™ MRPS31 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561219

Catalog No. PIPA561219

Description

Immunogen sequence: DLLGIIKGMK VELSTVNVRT TKPPKRRPLK SLEATLGRLR RATEYAPKKR IEPLSPELVA AASAVADSLP FDKQTTKS Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 67%.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.

Specifications

• Antigen: MRPS31
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPS31
• Gene Alias: 1500002D03Rik; 28S ribosomal protein S31, mitochondrial; AA960481; Imogen 38; Imogen38; Imogen44; Imogn38; islet mitochondrial antigen, 38 kD; mitochondrial ribosomal protein S31; Mitochondrial small ribosomal subunit protein mS31; Mrps31; MRP-S31; S31mt
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10240
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q92665
• Gene Symbols: MRPS31
• Immunogen: Recombinant protein corresponding to Human MRPS31. Recombinant protein control fragment (Product #RP-97913).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG