Invitrogen™ MRPS31 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103517

Catalog No. PIPA5103517

Description

Antibody detects endogenous levels of total MRPS31.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.

Specifications

• Antigen: MRPS31
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPS31
• Gene Alias: 1500002D03Rik; 28S ribosomal protein S31, mitochondrial; AA960481; Imogen 38; Imogen38; Imogen44; Imogn38; islet mitochondrial antigen, 38 kD; mitochondrial ribosomal protein S31; Mitochondrial small ribosomal subunit protein mS31; Mrps31; MRP-S31; S31mt
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10240
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q92665
• Gene Symbols: MRPS31
• Immunogen: A synthesized peptide derived from human MRPS31(Accession Q92665), corresponding to amino acid residues Y142-R192.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov