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Invitrogen™ MRVI1 Polyclonal Antibody
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Catalog No. PIPA552592
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PIPA552592 100 μL
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Catalog No. PIPA552592 Supplier Invitrogen™ Supplier No. PA552592
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Rabbit Polyclonal Antibody

Immunogen sequence: NLVGLKLPDL SEAAEQEKGL PSELSPAIEE EESKSGLDVM PNISDVLLRK LRVHRSLPGS APPLTEKEVE NVFVQLSLAF RNDSYTLESR INQAERERNL Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 90%.

This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is downregulated during lymphoid differentiation. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, few of which initiate translation at a non-AUG (CUG) start site.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRVI1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MRVI1
Gene Accession No. Q9Y6F6
Gene Alias BB115629; inositol 1,4,5-triphosphate receptor associated 1; inositol 1,4,5-triphosphate receptor associated 1; protein MRVI1; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate; inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate; IP3 receptor associated cGMP kinase substrate; IP3 receptor associated cGMP kinase substrate A; IP3 receptor associated cGMP kinase substrate B; IP3R-associated cGMP kinase substrate; IRAG; IRAG1; JAW1L; JAW1-related protein MRVI1; MRV integration site 1; MRVI1; murine retrovirus integration site 1 homolog; murine retrovirus integration site 1 protein; Protein MRVI1; retroviral integration site 1; Ris1
Gene Symbols MRVI1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MRVI1. Recombinant protein control fragment (Product #RP-89975).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10335
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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