MRVI1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA3851

Catalog No. 01-670-147

Description

PA3-851 detects CARP from mouse and bovine samples. PA3-851 has been successfully used in Western blot and immunocytochemistry procedures. The PA3-851 immunogen is a synthetic peptide corresponding to residues 93-107 of bovine IRAG.

This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is downregulated during lymphoid differentiation. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, few of which initiate translation at a non-AUG (CUG) start site.

Specifications

• Antigen: MRVI1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRVI1
• Gene Alias: BB115629; inositol 1,4,5-triphosphate receptor associated 1; inositol 1,4,5-triphosphate receptor associated 1; protein MRVI1; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate; inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate; IP3 receptor associated cGMP kinase substrate; IP3 receptor associated cGMP kinase substrate A; IP3 receptor associated cGMP kinase substrate B; IP3R-associated cGMP kinase substrate; IRAG; IRAG1; JAW1L; JAW1-related protein MRVI1; MRV integration site 1; MRVI1; murine retrovirus integration site 1 homolog; murine retrovirus integration site 1 protein; Protein MRVI1; retroviral integration site 1; Ris1
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Bovine, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Western Blot
• Concentration: Conc. Not Determined
• Formulation: whole serum with 0.05% sodium azide
• Gene Accession No.: Q9N1F0, Q9WUX5
• Gene Symbols: MRVI1
• Immunogen: Synthetic peptide corresponding to residues 93-107 of bovine IRAG.
• Regulatory Status: RUO
• Gene ID (Entrez): 17540, 281918
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid