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  5. Tocris Bioscience™ MS 15203

Tocris Bioscience™ MS 15203

Catalog No. 629925
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25 mg
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Catalog No. Quantity
62-992-5 25 mg
62-995 5 mg
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Catalog No. 62-992-5 Supplier Tocris Bioscience™ Supplier No. 6299/25

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

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Description

Potent and selective GPR171 partial agonist

MS 15203 is a potent and selective GPR171 partial agonist (EC50 = 90 nM; 28% inhibition of Forskolin activated adenylyl cyclase activity in rat hypothalamic membranes). Exhibits minimal binding to a panel of ∼70 GPCRs and 10 other receptors (<22% of radioligand displaced from the target receptors). Increases neuronal activity in the paraventricular nucleus. Increases food intake and body weight in mice.

Specifications

Chemical Name or Material 5-[(2-Methyl-1-oxo-2-propen-1-yl)amino]-1,3-benzenedicarboxylic acid
CAS 73912-52-4
Assay Percent Range >98%
Quantity 25 mg
Molecular Formula C12H11NO5
Formula Weight Observed MW: 249.22
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