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Tocris Bioscience™ MS 154N
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Catalog No. 73965
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73-965 5 mg
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Catalog No. 73-965 Supplier Tocris Bioscience™ Supplier No. 7396/5
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Description

Negative control for MS 154 (Cat No. 7395)

MS 154N is a negative control for MS 154 (Cat No. 7395). The compound exhibits high binding-affinity for WT and L858R-mutant EGFR (Kd values are 3 and 4.3 nM, respectively), but does not significantly induce degradation of EGFR mutants.

Specifications

Chemical Name or Material 3-(4-(3-((4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)piperazin-1-yl)-N-(8-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)octyl)propanamide
Quantity 5 mg
Target Active Degrader Negative Controls
Molecular Formula C47H56ClFN8O8
Purity 0.98
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