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  5. Tocris Bioscience™ MS 275

Tocris Bioscience™ MS 275
GREENER_CHOICE

Catalog No. 620850
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

HDAC (Class I) inhibitor

MS 275 is a class I HDAC inhibitor (IC50 values are 0.18, 0.74, 44.9 and >100 μM for HDAC1, 3, 8 and 6, respectively). Exhibits antiproliferative effects and induces apoptosis in a range of tumor cell lines in vitro and in vivo. Increases estrogen receptor α- and aromatase expression in breast cancer cells. Inhibits PCB-induced neuronal cell death by preventing HDAC3 binding and histone deacetylation within the synapsin-1 promoter.

Specifications

Chemical Name or Material (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate
CAS 209783-80-2
Assay Percent Range >99%
Quantity 50 mg
Molecular Formula C21H20N4O3
Formula Weight Observed MW: 376.41
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