Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Custom Products and Services
  4. Custom Enzymes and Inhibitors
  5. Tocris Bioscience™ MS 436

Tocris Bioscience™ MS 436

Potent and selective BRD4(1) inhibitor

Specifications

Purity >98%
Product Type MS 436
Molecular Weight (g/mol) 383.42
Inhibitors MS 436
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
51-735-0
View Documents
View Product Certificates
View Alternatives and Save Up to
Tocris Bioscience™
5173/50 		50 mg N/A N/A N/A
51-731-0
View Documents
View Product Certificates
View Alternatives and Save Up to
Tocris Bioscience™
5173/10 		10 mg N/A N/A N/A
Description

Description

Potent and selective BRD4 bromodomain inhibitor (Ki = 30 - 50 nM for the first bromodomain (BRD4(1)). Exhibits 10-fold selectivity for BRD4(1) over BRD4(2). Blocks BRD4 transcriptional activity in lipopolysaccharide-induced production of both nitric oxide and IL-6 in mouse macrophages (IC50 values are 3.8 and 4.9 μM, respectively). Attenuates melanoma cell proliferation in vitro.
Specifications

Specifications

>98%
MS 436
383.42
MS 436
Videos
SDS
Documents

Documents

Product Certifications

For Research Use Only

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.