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Description
Biological Activity: Potent and selective ASK1 inhibitor (IC50 = 93 nM). Selective for ASK1 over a panel of 210 kinases. Blocks LPS-induced ASK1 and p38 phosphorylation in cultured mouse astrocytes. Suppresses neuroinflammation in a mouse EAE model. Orally bioavailable and brain penetrant.
Storage: Store at 4°C.
Note: Inhibitors are guaranteed for 1 year from date of receipt.
Specifications
Specifications
| Product Type | Inhibitor |
| Target Proteins | ASK1 |
| CAS | 1124381-43-6 |
| Molecular Formula | C16H13F3N6O |
| Formula Weight | 362.41g/mol |
| Content And Storage | Store at 20°C |
| For Use With (Application) | Potent and selective ASK1 inhibitor |
| Quantity | 10 mg |
For Research Use Only
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