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Invitrogen™ MSC Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA584571
Description
Immunogen sequence: TGSVSDPEEM ELRGLQREYP VPASKRPPLR GVERSYASPS DNS.
MyoD-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many musclespecific terminal differentiation genes. MyoD complexes potently induce transcriptional activation, while musculin complexes bind adjacent to MyoD DNA-binding regions to represses MyoD activity, which then results in the delayed expression of muscle-specific genes. Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is down regulated during myogenesis and at the onset of terminal differentiation.
Specifications
MSC | |
Polyclonal | |
Unconjugated | |
MSC | |
ABF1; ABF-1; Activated B-cell factor 1; activated B-cell factor 1, homolog of mouse musculin; activated B-cell factor-1; bHLHa22; Class A basic helix-loop-helix protein 22; Msc; Musculin; myogenic repressor; Myor | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
9242 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot, Immunocytochemistry | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
O60682 | |
MSC | |
Recombinant protein corresponding to Human MSC. Recombinant protein control fragment (Product #RP-105246). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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