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Invitrogen™ MSC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA584571

Catalog No. PIPA584571


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Description

Description

Immunogen sequence: TGSVSDPEEM ELRGLQREYP VPASKRPPLR GVERSYASPS DNS.

MyoD-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many musclespecific terminal differentiation genes. MyoD complexes potently induce transcriptional activation, while musculin complexes bind adjacent to MyoD DNA-binding regions to represses MyoD activity, which then results in the delayed expression of muscle-specific genes. Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is down regulated during myogenesis and at the onset of terminal differentiation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MSC
Polyclonal
Unconjugated
MSC
ABF1; ABF-1; Activated B-cell factor 1; activated B-cell factor 1, homolog of mouse musculin; activated B-cell factor-1; bHLHa22; Class A basic helix-loop-helix protein 22; Msc; Musculin; myogenic repressor; Myor
Rabbit
Antigen affinity chromatography
RUO
9242
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot, Immunocytochemistry
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
O60682
MSC
Recombinant protein corresponding to Human MSC. Recombinant protein control fragment (Product #RP-105246).
100 μL
Primary
Human
Antibody
IgG
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