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Invitrogen™ MSC Polyclonal Antibody
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Catalog No. PIPA5118504
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100 μL
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PIPA5118504 100 μL
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Catalog No. PIPA5118504 Supplier Invitrogen™ Supplier No. PA5118504
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Musculin.

MyoD-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many musclespecific terminal differentiation genes. MyoD complexes potently induce transcriptional activation, while musculin complexes bind adjacent to MyoD DNA-binding regions to represses MyoD activity, which then results in the delayed expression of muscle-specific genes. Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is down regulated during myogenesis and at the onset of terminal differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MSC
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MSC
Gene Accession No. O60682
Gene Alias ABF1; ABF-1; Activated B-cell factor 1; activated B-cell factor 1, homolog of mouse musculin; activated B-cell factor-1; bHLHa22; Class A basic helix-loop-helix protein 22; Msc; Musculin; myogenic repressor; Myor
Gene Symbols MSC
Host Species Rabbit
Immunogen A synthesized peptide derived from human MSC(Accession O60682), corresponding to amino acid residues D147-A197.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 312897, 9242
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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