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Invitrogen™ MSH3 Recombinant Rabbit Monoclonal Antibody (RM405)
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Catalog No. PIMA536071
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100 μL
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Catalog No. Quantity
PIMA536071 100 μL
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Catalog No. PIMA536071 Supplier Invitrogen™ Supplier No. MA536071
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Description

Rabbit Recombinant Monoclonal Antibody

MSH3 Recombinant Monoclonal Antibody for Western Blot, IHC (P)

Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MSH3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone RM405
Concentration 0.04 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene MSH3
Gene Accession No. P20585
Gene Alias D13Em1; Divergent upstream protein; DNA mismatch repair protein Msh3; DUC1; DUG; DUP; hMSH3; Mismatch repair protein 1; MRP1; MSH3; mutS homolog 3; mutS homolog 3 (E. coli); protein repair-1; Protein repair-3; REP-1; Rep3; Rep-3
Gene Symbols MSH3
Host Species Rabbit
Immunogen A peptide corresponding to residues near the N-terminus of human MSH3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4437
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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