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MSH3 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501570031
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Catalog No. Quantity
50-157-0031 10 μL
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Catalog No. 50-157-0031 Supplier Bethyl Laboratories, Inc Supplier No. A305287AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

Specifications

Antigen MSH3
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene MSH3
Gene Accession No. P20585
Gene Alias DUP, MRP1, DNA mismatch repair protein Msh3, divergent upstream protein, hMSH3, mismatch repair protein 1
Gene Symbols MSH3
Host Species Rabbit
Immunogen Between 1025 and 1075
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4437
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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