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MSH3 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986222
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Catalog No. Quantity
50-198-6222 100 μL
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Catalog No. 50-198-6222 Supplier Bioss Supplier No. BS4919R
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Description

Rabbit Polyclonal Antibody

Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

Specifications

Antigen MSH3
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene MSH3
Gene Accession No. P20585
Gene Alias D13Em1; Divergent upstream protein; DNA mismatch repair protein Msh3; DUC1; DUG; DUP; hMSH3; Mismatch repair protein 1; MRP1; MSH3; mutS homolog 3; mutS homolog 3 (E. coli); Protein repair-1; Protein repair-3; REP-1; Rep3; Rep-3
Gene Symbols MSH3
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human MSH3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4437
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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