MSH6 Monoclonal Antibody (OTI5D1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA807929

Catalog No. 50-168-1849

Description

Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, domitly inherited disease associated with marked increase in cancer susceptibility. it is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.

Specifications

• Antigen: MSH6
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P52701
• Gene Symbols: MSH6
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-280 of human MSH6 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI5D1
• Conjugate: Unconjugated
• Gene: MSH6
• Gene Alias: GTBP, GTMBP, HNPCC5, HSAP, p160
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2956
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid