Invitrogen™ MSH6 Monoclonal Antibody (SP93)

Rabbit Monoclonal Antibody

Supplier:  Invitrogen™ MA516380

Catalog No. PIMA516380

Description

Heat-mediated antigen retrieval is recommended prior to staining, using a 1mM EDTA buffer, pH 8.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is rectal carcinoma.

The DNA mismatch repair MSH2/MSH6 heterodimer is responsible for the detection of DNA damage, and may promote apoptosis in normal cells, thus protecting mammals from ultraviolet-induced malignant transformation and hence the prevention of skin cancer.

Specifications

• Antigen: MSH6
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: MSH6
• Gene Alias: AU044881; AW550279; cb326; DNA mismatch repair protein Msh6; g/T mismatch-binding protein; GTBP; GTMBP; hMSH6; HNPCC5; HSAP; LOC100360342; mismatch repair protein Msh6; Msh6; mutS (E. coli) homolog 6; MutS alpha 160kDa subunit; mutS homolog 6; mutS homolog 6 (E. coli); MutS protein homolog 6; MutS-alpha 160 kDa subunit; MutS-alpha 160kDa subunit; p160; rCG61559-like; Sperm associated protein; sperm-associated protein; wu:fb36c12
• Host Species: Rabbit
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 2956
• Content And Storage: 4°C
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: SP93
• Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.6
• Gene Accession No.: P52701
• Gene Symbols: MSH6
• Immunogen: Synthetic peptide corresponding to internal region of human MSH6 protein.
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG