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Invitrogen™ MSI2 Monoclonal Antibody (3B6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA522987

Catalog No. PIMA522987


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Description

Description

Peptide Sequence: MEANGSQGTS GSANDSQHDP GKMFIGGLSW QTSPDSLRDY FSKFGEIREC MVMRDPTTKR SRGFGFVTFA DPASVDKVLG QPHHELDSKT IDPKVAFPRR AQPKMVTRTK KIFVGGLSAN TVVEDVKQYF EQFGKVEDAM LMFDKTTNRH RGFGFVTFEN EDVVEKVCEI HFHEINNKMV ECKKAQPKEV MFPPGTRGRA RGLPYTMDAF MLGMGMLGYP NFVATYGRGY PGFAPSYGYQ FPGFPAAAYG PVAAAAVAAA RGSGSNPARP GGFPGANSPG PVADLYGPAS QDSGVGNYIS AASPQPGSGF GHGIAGPLIA TAFTNGYH.

Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MSI2
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.4
Q96DH6
MSI2
MSI2 (AAH01526, 1 a.a. ~ 328 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
100 μg
Primary
Human
Antibody
IgG2b κ
ELISA, Immunoprecipitation, Western Blot
3B6
Unconjugated
MSI2
1700105C15Rik; AI451722; AI563628; AW489193; MSI2; Msi2h; musashi homolog 2; musashi RNA binding protein 2; musashi RNA-binding protein 2; Musashi2; musashi-2; RGD1560397; RNA-binding protein Musashi homolog 2
Mouse
Affinity Chromatography
RUO
124540
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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