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Invitrogen™ MSI2 Recombinant Rabbit Monoclonal Antibody (7L4E9)
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Catalog No. PIMA538016
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PIMA538016 100 μL
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Catalog No. PIMA538016 Supplier Invitrogen™ Supplier No. MA538016
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: HeLa, HT-29, PC-12, MCF7, Mouse brain, Rat brain Immunogen sequence: ARGLPYTMDA FMLGMGMLGY PNFVATYGRG YPGFAPSYGY QFPGFPAAAY GPVAAAAVAA ARGSGSNPAR PGGFPGANSP GPVADLYGPA SQDSGVGNYI S.

Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MSI2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 7L4E9
Concentration 0.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MSI2
Gene Accession No. Q920Q6, Q96DH6
Gene Alias 1700105C15Rik; AI451722; AI563628; AW489193; MSI2; Msi2h; musashi homolog 2; musashi RNA binding protein 2; musashi RNA-binding protein 2; Musashi2; musashi-2; RGD1560397; RNA-binding protein Musashi homolog 2
Gene Symbols MSI2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Musashi-2 (MSI2) (Q96DH6).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 124540, 360596, 76626
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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