Invitrogen™ MSI2 Recombinant Rabbit Monoclonal Antibody (7L4E9)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538016

Catalog No. PIMA538016

Description

Positive Samples: HeLa, HT-29, PC-12, MCF7, Mouse brain, Rat brain Immunogen sequence: ARGLPYTMDA FMLGMGMLGY PNFVATYGRG YPGFAPSYGY QFPGFPAAAY GPVAAAAVAA ARGSGSNPAR PGGFPGANSP GPVADLYGPA SQDSGVGNYI S.

Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.

Specifications

• Antigen: MSI2
• Classification: Recombinant Monoclonal
• Concentration: 0.8 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q920Q6, Q96DH6
• Gene Symbols: MSI2
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Musashi-2 (MSI2) (Q96DH6).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 7L4E9
• Conjugate: Unconjugated
• Gene: MSI2
• Gene Alias: 1700105C15Rik; AI451722; AI563628; AW489193; MSI2; Msi2h; musashi homolog 2; musashi RNA binding protein 2; musashi RNA-binding protein 2; Musashi2; musashi-2; RGD1560397; RNA-binding protein Musashi homolog 2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 124540, 360596, 76626
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid