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Invitrogen™ MSI2 Recombinant Rabbit Monoclonal Antibody (RM422)
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Catalog No. PIMA536217
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100 μL
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PIMA536217 100 μL
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Catalog No. PIMA536217 Supplier Invitrogen™ Supplier No. MA536217
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Description

Rabbit Recombinant Monoclonal Antibody

MA5-36217 reacts to human Musashi 2. This antibody may also react to mouse or rat Musashi 2, as predicted by immunogen homology.

Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MSI2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone RM422
Concentration 0.02 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene MSI2
Gene Accession No. Q96DH6
Gene Alias 1700105C15Rik; AI451722; AI563628; AW489193; MSI2; Msi2h; musashi homolog 2; musashi RNA binding protein 2; musashi RNA-binding protein 2; Musashi2; musashi-2; RGD1560397; RNA-binding protein Musashi homolog 2
Gene Symbols MSI2
Host Species Rabbit
Immunogen A peptide corresponding to the internal region of human Musashi 2 (aa 200-300).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 124540
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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