Invitrogen™ MSK2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587658

Catalog No. PIPA587658

Description

Immunogen sequence: WLQDGSARSS PPLRTPDVLE SSGPAVRSGL NATFMAFNRG KREGFFLKSV ENAPLAKRRK QKLRSATASR RGSPAPANPG RAPVASKGAP RRANGPLPPS Positive Samples: HeLa, SH-SY5Y, HL-60, BT-474, Mouse heart, Mouse kidney, Mouse liver; Cellular Location: Nucleus.

RPS6KA4 (MSK2) is a serine/threonine protein kinase that is essential for the regulation of various cellular processes. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. RPS6KA4 contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Specifications

• Antigen: MSK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rps6ka4
• Gene Alias: 1110069D02Rik; 90 kDa ribosomal protein S6 kinase 4; 90kDa; AI848992; Ccdc88b; coiled-coil domain containing 88B; EC 2.7.11.1; kinase MSK2; KS6A4; mitogen- and stress-activated protein kinase 2; mitogen- and stress-activated protein kinase-2; mMSK2; MSK2; Nuclear mitogen- and stress-activated protein kinase 2; ribosomal protein kinase B; ribosomal protein S6 kinase A4; ribosomal protein S6 kinase alpha 4; ribosomal protein S6 kinase alpha-4; ribosomal protein S6 kinase, 90kD, polypeptide 4; ribosomal protein S6 kinase, 90kDa, polypeptide 4; ribosomal protein S6 kinase, polypeptide 4; RLSK; RPS6KA4; RSKB; RSK-B; RSK-like protein kinase; S6K-alpha-4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56613, 8986
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.04 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: O75676, Q9Z2B9
• Gene Symbols: Rps6ka4
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 673-772 of human RPS6KA4 (NP_0039331).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG