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MSL2 Monoclonal Antibody (OTI3B11), TrueMAB™, OriGene
SDP

Catalog No. 501683887
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100 μL
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Catalog No. Quantity
50-168-3887 100 μL
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Catalog No. 50-168-3887 Supplier OriGene Supplier No. TA811188
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Description

Mouse Monoclonal Antibody

Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at ′Lys-35′ (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at ′Lys-4′ (H3K4me) and ′Lys-79′ (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.

Specifications

Antigen MSL2
Applications Western Blot
Classification Monoclonal
Clone OTI3B11
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene MSL2
Gene Accession No. Q9HCI7
Gene Alias MSL-2, MSL2L1, RNF184
Gene Symbols MSL2
Host Species Mouse
Immunogen Full length human recombit protein of human MSL2 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55167
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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