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Invitrogen™ MSL2 Monoclonal Antibody (OTI4G7)
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Catalog No. PIMA527413
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100 μL
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Catalog No. Quantity
PIMA527413 100 μL
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Catalog No. PIMA527413 Supplier Invitrogen™ Supplier No. MA527413
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Description

Mouse Monoclonal Antibody

MSL2 Monoclonal Antibody for Western Blot

Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen MSL2
Applications Western Blot
Classification Monoclonal
Clone OTI4G7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MSL2
Gene Accession No. Q9HCI7
Gene Alias E130103E02Rik; E3 ubiquitin-protein ligase MSL2; E3 ubiquitin-protein transferase MSL2; Kiaa1585; male-specific lethal 2 homolog; male-specific lethal 2 homolog (Drosophila); male-specific lethal 2-like 1; Male-specific lethal-2 homolog; Male-specific lethal-2 homolog 1; MSL2; MSL-2; Msl2l1; MSL2-like 1; RGD1310355; ring finger protein 184; Rnf184
Gene Symbols MSL2
Host Species Mouse
Immunogen Full length human recombinant protein of MSL2 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55167
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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