Invitrogen™ MSRA Monoclonal Antibody (C6), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA550974

Catalog No. FEMA550974

Description

Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and a 1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimer's disease in mammals.

Specifications

• Antigen: MSRA
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Accession No.: Q923M1, Q9UJ68
• Gene Symbols: Msra
• Immunogen: Recombinant Human MSRA protein, Ala27-Lys235 (Accession #Q9UJ68).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat, Pig
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Clone: C6
• Conjugate: Unconjugated
• Gene: Msra
• Gene Alias: 2310045J23Rik; 6530413P12Rik; cytosolic methionine-S-sulfoxide reductase; methionine sulfoxide reductase A; mitochondrial peptide methionine sulfoxide reductase; Msra; MSR-A; peptide met (O) reductase; peptide Met(O) reductase; peptide methionine sulfoxide reductase; peptide-methionine (S)-S-oxide reductase; PMSR; protein-methionine-S-oxide reductase
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 100152960, 29447, 4482
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid