Invitrogen™ MSRA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA582845

Catalog No. PIPA582845

Description

Immunogen sequence: ASNIVSPQEA LPGRKEQTPV AAKHHVNGNR TVEPFPEGTQ MAVFGMGCFW GAERKFWVLK GVYSTQVG.

Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and a 1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimer's disease in mammals.

Specifications

• Antigen: MSRA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Msra
• Gene Alias: 2310045J23Rik; 6530413P12Rik; cytosolic methionine-S-sulfoxide reductase; methionine sulfoxide reductase A; mitochondrial peptide methionine sulfoxide reductase; Msra; MSR-A; peptide met (O) reductase; peptide Met(O) reductase; peptide methionine sulfoxide reductase; peptide-methionine (S)-S-oxide reductase; PMSR; protein-methionine-S-oxide reductase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4482
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.10 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UJ68
• Gene Symbols: Msra
• Immunogen: Recombinant protein corresponding to Human MSRA. Recombinant protein control fragment (Product #RP-93911).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov